منابع مشابه
Transposable Elements: No More 'Junk DNA'
Since the advent of whole-genome sequencing, transposable elements (TEs), just thought to be 'junk' DNA, have been noticed because of their numerous copies in various eukaryotic genomes. Many studies about TEs have been conducted to discover their functions in their host genomes. Based on the results of those studies, it has been generally accepted that they have a function to cause genomic and...
متن کاملPerspective : Transposable Elements , Parasitic Dna , and Genome
The nature of the role played by mobile elements in host genome evolution is reassessed considering numerous recent developments in many areas of biology. It is argued that easy popular appellations such as ‘‘selfish DNA’’ and ‘‘junk DNA’’ may be either inaccurate or misleading and that a more enlightened view of the transposable element-host relationship encompasses a continuum from extreme pa...
متن کاملA brief history of the status of transposable elements: from junk DNA to major players in evolution.
The idea that some genetic factors are able to move around chromosomes emerged more than 60 years ago when Barbara McClintock first suggested that such elements existed and had a major role in controlling gene expression and that they also have had a major influence in reshaping genomes in evolution. It was many years, however, before the accumulation of data and theories showed that this latte...
متن کاملAlu Mobile Elements: From Junk DNA to Genomic Gems
Alus, the short interspersed repeated sequences (SINEs), are retrotransposons that litter the human genomes and have long been considered junk DNA. However, recent findings that these mobile elements are transcribed, both as distinct RNA polymerase III transcripts and as a part of RNA polymerase II transcripts, suggest biological functions and refute the notion that Alus are biologically unimpo...
متن کاملTurning gold into ‘junk’: transposable elements utilize central proteins of cellular networks
The numerous discovered cases of domesticated transposable element (TE) proteins led to the recognition that TEs are a significant source of evolutionary innovation. However, much less is known about the reverse process, whether and to what degree the evolution of TEs is influenced by the genome of their hosts. We addressed this issue by searching for cases of incorporation of host genes into t...
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ژورنال
عنوان ژورنال: Genomics & Informatics
سال: 2012
ISSN: 1598-866X,2234-0742
DOI: 10.5808/gi.2012.10.4.226